Genprex Appoints John N. Bonfiglio, PhD, to Board of Directors

Genprex, Inc. (NASDAQ: GNPX) a clinical-stage gene therapy company developing a new approach to treating cancer based upon a novel proprietary technology platform, announced today the appointment of John N. Bonfiglio, PhD, to the company’s Board of Directors. In recent years, Dr. Bonfiglio served as President and CEO of Oragenics, Inc. and most recently as President and COO of TapImmune, Inc., where he helped lay the groundwork for a successful merger with Marker Therapeutics, Inc. in October 2018 by up-listing TapImmune to Nasdaq and starting a robust clinical program in breast and ovarian cancers. John’s more than 30 years of experience in the pharmaceutical and biotechnology industries will enable the Genprex Board and management team to draw on his expertise to help guide Genprex as it continues to grow.

“I am honored and excited to join Genprex’s Board of Directors,” Dr. Bonfiglio said. “I see tremendous potential for Genprex. In my opinion, Genprex’s clinical and pre-clinical research show that its lead drug candidate, Oncoprex™ immunogene therapy, can potentially work synergistically in combination with targeted therapies and immunotherapies to treat cancer patients outside of the population normally targeted by these cancer therapies. Clinical exploration of these areas could lead to market expansion and to new patient populations with unmet medical needs. The market potential for these new combination therapies is very attractive.”

Dr. Bonfiglio began his career as a scientist with Allergan, Inc. before moving into project and business development. Over the course of his career he has held several executive leadership positions including President and CEO at Peregrine Pharmaceuticals, Inc., Executive Vice President and COO of Cypress Bioscience, Inc., President and CEO of The Immune Response Corporation and the President and CEO of Argos Therapeutics, Inc., among others. In those positions, he has succeeded in raising capital, lowering burn rates, setting corporate strategies, controlling corporate spending and managing clinical trials. Throughout his career he has helped raise more than $150 million in capital while helping companies relist and up-list with national securities exchanges. Recently, he joined the Board of Directors of GT Biopharma, Inc., adding to his significant experience in the immuno-oncology field.

“We are excited that Dr. Bonfiglio has accepted our invitation to join our Board of Directors,” said Rodney Varner, Genprex’s Chief Executive Officer and Chairman. “His experience and expertise are impressive. His background with other biotechnology companies will provide us with extensive knowledge and resources. We believe that Dr. Bonfiglio will make a great contribution to our future success.” 

Dr. Bonfiglio’s appointment to the Board is the latest high-profile addition to Genprex as the company continues to grow. In October 2018, Genprex appointed Jan Stephens, RN, as the company’s Vice President of Clinical Operations.

About Genprex, Inc.

Genprex, Inc. is a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. The Company’s lead product candidate, GPX-001 (quaratusugene ozeplasmid), is being evaluated as a treatment for non-small cell lung cancer (NSCLC). GPX-001 has a multimodal mechanism of action that has been shown to interrupt cell signaling pathways that cause replication and proliferation of cancer cells; re-establish pathways for apoptosis, or programmed cell death, in cancer cells; and modulate the immune response against cancer cells. GPX-001 has also been shown to block mechanisms that create drug resistance. In January 2020, the U.S. Food and Drug Administration granted Fast Track Designation for GPX-001 for NSCLC in combination therapy with osimertinib (AstraZeneca’s Tagrisso®) for patients with EFGR mutations whose tumors progressed after treatment with osimertinib aloneFor more information, please visit the Company’s web site at www.genprex.com or follow Genprex on TwitterFacebook and LinkedIn.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding the effect of Genprex’s product candidates, alone and in combination with other therapies, on cancer and diabetes, regarding potential, current and planned clinical trials, regarding the Company’s future growth and financial status and regarding our commercial partnerships and intellectual property licenses. Risks that contribute to the uncertain nature of the forward-looking statements include the presence and level of the effect of our product candidates, alone and in combination with other therapies, on cancer; the timing and success of our clinical trials and planned clinical trials of GPX-001, alone and in combination with targeted therapies and/or immunotherapies, and whether our other potential product candidates, including GPX-002, our gene therapy in diabetes, advance into clinical trials; the success of our strategic partnerships, including those relating to manufacturing of our product candidates; the timing and success at all of obtaining FDA approval of GPX-001 and our other potential product candidates including whether we receive fast track or similar regulatory designations; costs associated with developing our product candidates and whether patents will ever be issued under patent applications that are the subject of our license agreements. These and other risks and uncertainties are described more fully under the caption “Risk Factors” and elsewhere in our filings and reports with the United States Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. We undertake no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Media Contact
Genprex Media Relations
(877) 774-GNPX (4679) ext. #3
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